Interests

Metabolism

Metabolism encompasses all chemical reactions that are necessary for life. I am broadly interesed in the mechanisms by which cells determine nutrient levels and subsequently act upon this information. I am also interested in how metabolism is altered in disease.

Stress Responses

Cells have evolved mechanisms to alleviate various types of stress, including metabolic, protein, and DNA damage. These responses are critical for tumorigenesis. I am interested in how cells regulate these stress responses, the impact of these responses to the development of tumors, and the role of these responses in the tumor microenvironment.

Gene Regulation

Gene expression is controlled at many different levels, ranging from chromatin to transcription factors to signaling pathways. I am interested in how this process is influenced by metabolism, environmental factors, and stress in healthy and disease states.